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SAVING AND TRANSFORMING LIVES Help us significantly improve the lives of people with Down syndrome through Research, Medical Care, Education and Advocacy.

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Save the Date! 2021 Be Beautiful Be Yourself Fashion Show

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Making an Impact

through a network of affiliate organizations that work closely together on a daily basis to significantly improve the lives of people with Down syndrome.

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unique patients provided with medical care
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scientists supported by Global

Linda Crnic Institute for Down Syndrome

Established in 2008, the Institute is the first academic home for Down syndrome research in the United States.

Anna and John J. Sie Center for Down Syndrome

The Sie Center is one of the largest in the United States that specializes in treating children with Down syndrome.

Adult Down Syndrome Clinic at Denver Health

Providing quality health care to adolescents and adults with Down Syndrome, education for their families and caregivers.

Alzheimer's and Cognition Center

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Supporting the Down Syndrome Community

Get The Facts

Learn about the causes of Down syndrome along with other facts and FAQs.

Find Medical Care Centers

Find a medical care center near you using our searchable map.

Down Syndrome WorldTM

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Find Local Organizations

Find a Down Syndrome organization in your area to connect with others.

It's time to change the status quo Down syndrome is the least funded genetic condition despite being the most frequent.

Did You Know?

The average life expectancy for a person with Down syndrome is nearly 60 years old. Some people with Down syndrome have lived into their 80s.

Did You Know?

An increasing number of adults with Down syndrome in the U.S. are living independently with limited assistance from family members or the state. A small percentage are able to live entirely independently.

Did You Know?

By law, people with Down syndrome must be provided a free, appropriate education through their public-school system.

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Honor Someone

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Trending News

Katy Teen with Down Syndrome Helps Raise $2.5M on Fashion Show Runway

Two years ago, Ally attended the Be Beautiful Be Yourself fashion show with her dad, Mark McCollam. She immediately expressed interest in being involved with the show. This year, she got her turn. Last weekend, Ally and her family set out to Denver, Colorado. The young girl had earned her spot among 22 models to participate in the Be Beautiful Be Yourself fashion show.

Ally rocked the runway with actress Mikaela Hoover. The event raised $2.5 million for the Global Down Syndrome Foundation. This is no small achievement - according to the foundation, Down syndrome is the least-funded genetic condition in the United States.

Babies with Down syndrome are put on center stage in the U.S. abortion fight

Budget Chairman Tom Cole Announces Historic NIH Budget Increase at the Global Down Syndrome